Experimental neurocysticercosis and demyelination
نویسندگان
چکیده
منابع مشابه
MR imaging of experimental demyelination.
Seventeen rabbit sciatic nerves undergoing experimental demyelination and 17 control nerves were imaged in vivo with a 0.3-T MR imaging system using a silicone chamber wrapped around the nerves to isolate them from surrounding tissues. Three pulse sequences were used for each nerve: (1) spin-echo 500/28 (TR/TE), (2) spin-echo 2000/56, and (3) inversion recovery 1000/300/30 (TR/TI/TE). Image int...
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Because of the reported absence of demyelination in some animals with neurological signs of experimental allergic encephalomyelitis (EAE), it has been suggested that these signs are not due to demyelination. The present study demonstrates that there is ample demyelination in the central nervous system (CNS) and peripheral nervous system (PNS) to account for the neurological signs in rats with m...
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The neuropeptide galanin is widely expressed by many differing subsets of neurons in the nervous system. There is a marked upregulation in the levels of the peptide in a variety of nerve injury models and in the basal forebrain of humans with Alzheimer's disease. Here we demonstrate that galanin expression is specifically and markedly upregulated in microglia both in multiple sclerosis (MS) les...
متن کاملTaenia solium: Development of an Experimental Model of Porcine Neurocysticercosis
Human neurocysticercosis (NC) is caused by the establishment of Taenia solium larvae in the central nervous system. NC is a severe disease still affecting the population in developing countries of Latin America, Asia, and Africa. While great improvements have been made on NC diagnosis, treatment, and prevention, the management of patients affected by extraparenchymal parasites remains a challen...
متن کاملExperimental neurocysticercosis: absence of IL-4 induces lower encephalitis.
Methods BALB/c (WT) and BALB/c (IL-4-KO) mice were inoculated intracranially with Taenia crassiceps cysticerci and euthanized at 7, 30, 60 and 90 days later, the encephala removed and histopathologically analyzed. Results The absence of IL-4 induced greater parasitism. In the initial phase of the infection, IL-4-KO showed a lower intensity in the inflammatory infiltration of polimorphonuclear...
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ژورنال
عنوان ژورنال: Arquivos de Neuro-Psiquiatria
سال: 2020
ISSN: 1678-4227,0004-282X
DOI: 10.1590/0004-282x20200034